3D Architectural Rendering and gaming.
First off, yes, the case isn't suitable for this build. But it was my very first case, and loved it so much, it has been a running gag to make everything I'm using into it.
The power supply isn't properly screwed to the case as it doesn't really fit.
The 4th GPU blocks the USB 3.0 20 pin connector, so front USB 3.0 ports don't work (they did with my old mobo)
Everything else works just fine.