I built this system to replace my venerable Dell Studio 540, vintage 2008 (Intel Q8200 2.33 GHz, 6 GB ram, ATI Radeon HD3400 graphics, 500 GB SSD, 1 TB HDD, Win10 Pro). My primary goal was to see if I could actually build a working computer at my age - 79 years. Secondary goals were to make a system usable in my engineering consulting business and support my video editing hobby. Over the last several years I have been watching build videos produced by Carey Holzman to understand what I was getting into. His videos helped me pick parts from reputable vendors and determine the build sequence. My first attempt, Build 1.0, was a learning experience. After careful assembly, upon first power ON the fans spun but no POST. The motherboard for Build 1.0 was the ASUS Prime Z-270A and it only has 4 diagnostic LEDs, and the DRAM LED was lit. I started swapping memory cards around the four slots and discovered that one of the memory channels was bad. As long as I plugged my memory into the other channel it went through POST with no problem. I returned the board to Amazon (zero problems and very easy thankfully) and decided I needed a board with more diagnostic capability so I ordered the ASUS Maximus IX Hero Z270. I then reassembled the system (Build 2.0). It powered up the first time and completed a successful POST. I updated the BIOS, installed Win10 Pro, and used the method from Ten Forums to move the User Profile to D: (SATA SSD), leaving C: (NVME SSD) for System and Programs. Finally I moved my data folders/files from the old Dell and reinstalled all of my applications. I'm using the on-board graphics with my old 22" display - OK for now. All in all I feel I successfully accomplished my goals and now have a very capable system that will last me for awhile. Next year I will add a graphics board (probably Nvidia 1070 and a 4K monitor). My motor skills are adequate for this job but I did recall my days working on wire wrap back planes with the .025 pins and 0.1 spacing - couldn't do that today!
This is a BIG air cooler but I didn't like the liquid AIO devices. You'll notice that I replaced the 1st fan with a smaller 120mm one. The fans supplied are 140 X150, and the 1st fan hit the heat spreader on the memory and extended above the cooler, just about touching the side of the case. It looked butt ugly to me. I replaced that fan with a 120 X120. The bigger fan was placed on the front of the case.
The ASUS software provides many options for tuning the system - a big plus since I have no experience with over clocking.